It takes a more general form in Hilgard's neo-dissociation theory of hypnotic phenomena and also in Jung's theory of the collective unconscious. Dissociation is a concept introduced by Pierre Janet for splitting consciousness due to traumatic events or during hypnosis. The first represents psychic contents which are subliminal for their low energy, the second subliminal contents which are inaccessible to consciousness because they are dissociated in the subliminal region. However, people with no family history of epidermolytic hyperkeratosis are often affected, and a spontaneous gene mutation is thought to account for approximately half of all cases of the condition.Abstract The study of unconscious processes leads to the hypothesis of the limit of consciousness, which involves two main kinds of psychic activity. In rare cases, the KRT10 gene can be inherited in an autosomal recessive pattern, such that an individual must inherit a copy of a gene mutation from both parents in order to be affected. If one parent is affected, each child has a 50% chance of inheriting the disease. This means that one copy of a mutated gene is able to cause the disorder and can be inherited from either parent. It is not known how these mutations lead to hyperkeratosis.Įpidermolytic hyperkeratosis is usually inherited in an autosomal dominant pattern. ![]() As a result, the skin may blister and become damaged easily, even in response to mild injury. A mutation in one of these genes can result in modified keratin proteins and affect the strength of the keratin in the epidermis. These genes are involved in the production of the keratin proteins 1 and 10, respectively, which are present in the epidermis of the skin and provide strength. A widespread, thick, and scaly area is a characteristic sign of this type of hyperkeratosis.Ī mutation in the KRT1 or KRT10 genes can cause epidermolytic hyperkeratosis. The signs of inherited keratosis usually begin in infancy or childhood and can affect large areas of the body. In such a case, it may be caused by an inherited condition. In some cases, hyperkeratosis can occur on skin that has not been irritated or previously exposed to an infection. This is because ill-fitting dentures may rub against the skin in the mouth and cause the condition. People who have dentures are more likely to have problems related to hyperkeratosis in the mouth. Inherited conditions: Other inherited hyperkeratosis conditions involve the development of thick and scaly skin caused by genetic susceptibility.Seborrheic keratosis: This condition is associated with small brown or black spots anywhere on the skin with no known cause.Actinic keratosis: Actinic keratosis is characterized by flat, red patches of skin caused by excessive exposure to ultraviolet (UV) radiation from sunlight.Lichen planus: This condition is characterized by lacy white patches inside the mouth and/or itchy, scaly, and violaceous patches on the skin caused by an abnormal immune system response.Chronic eczema: Chronic eczema is associated with inflammation of the skin caused by allergies, irritants, or other triggers.Calluses: Calluses are an accumulation of dead skin cells due to repeated friction or pressure on the soles of the feet, palms of the hands, or other areas.Corns: Corns are a build-up of dead skin cells caused by repeated friction or pressure to the toes or other areas.Warts: Warts are small bumps caused by an infection with human papillomavirus (HPV) that can arise anywhere on the skin, often on the hands and feet.As such, the various forms with their likely causes are listed below: The type of hyperkeratosis is an important factor when discussing the cause of the condition. ![]() Image Credit: Dermatology11 / Causes by type of hyperkeratosis ![]() The type of skin thickening found in hyperkeratosis is often a natural response to pressure, rubbing, or irritation of the skin, although there are a number of possible causes. Keratin helps to protect the body against infiltration by water and other chemical and biological agents with which it comes in contact every day. Hyperkeratosis is the thickening of the outer layer of the skin, which contains a protein known as keratin.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |